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Ward J.A., Romartinez-Alonso B., Kay D.F., Bellamy-Carter J.,​ Thurairajah B., Basran J., Kwon H., Leney A.C., Macip S., Roversi P., Muskett F.W., Doveston R.G. Characterizing the protein–protein interaction between MDM2 and 14-3-3σ; proof of concept for small molecule stabilization. Journal Biological Chemistry (2024) DOI:



Verhoef C.J.A., Kay D.F, van Dijck L., Doveston R.G. Brunsveld L., Leney A.C. and Peter J. Cossar. Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry. Chemical Science (2023) 

Sound J.K., Bellamy-Carter J., Leney A.C. The increasing role of structural proteomics in cyanobacteria. Essays Biochem (2023) EBC20220095.


Adoni K.R., Cunningham D.L., Heath J.K., Leney A.C.. FAIMS enhances the detection of PTM crosstalk sites. Journal of Proteome Research (2022) 21 (4), 930-939.

Bellamy-Carter J., Sound J.K., Leney A.C. Probing heavy metal binding to phycobiliproteins. The FEBS journal (2022) In Press.


Cooper H.J., Leney A.C. Structural proteomics and protein complexes-special issue. Proteomics (2021) 21 (21-22), 2000286.

Sound J.K., Peters A., Bellamy-Carter J., Rad-Menendez C., MacKechnie K., Green D.H., Leney A.C. Rapid cyanobacteria species identification with high sensitivity using native mass spectrometry. Analytical Chemistry (2021) 93, 42, 14293–14299

Bellamy-Carter J., Mohata M., Falcicchio M., Basran J., Higuchi Y., Doveston R. G., Leney A.C. Discovering protein–protein interaction stabilisers by native mass spectrometry. Chemical Science (2021) 12 (32), 10724-10731.


Muha V., Williamson R., Hills R., McNeilly A.D., McWilliams T.G., Alonso J., Schimpl M., Leney A.C., Heck A.J.R., Sutherland C., Read K.D., McCrimmon R.J., Brooks S.P., van Aalten D.M.F. Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice. Open Biol. (2019) In Press.

Hughes G., Hall S., Laxton C., Sridhar P., Mahadi A., Hatton C., Piggot T., Wotherspoon P., Leney A.C., Ward D., Jamshad M., Spana V., Cadby I., Harding C., Isom G., Bryant J., Parr R., Yakub Y., Jeeves M., Huber D., Henderson I., Clifton L., Lovering A., Knowles T. Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system. Nat. Microbiol. (2019) 4: 1692–1705.

Leney A.C. Subunit pI can influence protein complex dissociation characteristics. J. Am. Soc. Mass Spectrom. (2019). doi: 10.1007/s13361-019-02198-3.

Tamara S., Hoeka M., Scheltema R.A., Leney A.C.*, Heck A.J.R.* A colorful pallet of B-phycoerythrin proteoforms exposed by a multimodal mass spectrometry approach. Chem. (2019) 5(5): 1302-1317.



Laarse S.A.M+, Leney A.C.+, Heck A.J.R. Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe. FEBS J. (2018)

Leney A.C.*, Tschanz A., Heck A.J.R. Connecting color with assembly in the fluorescent B-phycoerythrin protein complex. FEBS J. (2018) 285(1): 178-187.



Tamara S., Scheltema R.A., Heck A.J.R.*, Leney A.C.* Phosphate transfer in activated protein complexes reveal interaction sites. Angew. Chem. (2017) 129(44): 13829-13832.

Leney A.C., Atmioui D.E., Wu W., Ovaa H., Heck A.J.R. Elucidating cross-talk mechanisms between phosphorylation and O-GlcNAcylation. Prot. Nat. Acad. Sci. (2017) 114(35): 7255-7261.

Leney A.C., Rafie K., van Aalten D.M.F., Heck A.J.R. Direct Monitoring of protein O-GlcNAcylation by high-resolution native mass spectrometry. ACS Chem. Biol. (2017) 12(8): 2078-2084.


Leney A.C., Heck A.J.R. Native mass spectrometry: what is in the name? J. Am. Soc. Mass Spectrom. (2017) 28(1): 5-13.



Lössl P., Brunner A.M., Lui F., Leney A.C., Yamashita M., Scheltema R.A., Heck A.J.R. Deciphering the interplay among multi-site phosphorylation, interaction dynamics and conformational transitions in a tripartite protein system. ACS Cent. Sci. (2016) 2(7):445-455.


Marino F., Bern M., Mommen G.P.M., Leney A.C., Bonvin A.M.J.J., van Els C.A.C.M., Becker C., Heck A.J.R. Extended O-GlcNAc on HLA class-I-bound peptides. J. Am. Chem. Soc. (2015) 137(34):10922-10925.

Leney A.C., Darestani R.R., Li J., Nikjah S., Kitova E.N., Zou C., Cairo C.W., Xiong Z.J., Privé G.G., Klassen J.S. Picodiscs for facile protein-glycolipid analysis. Anal. Chem. (2015) 87(8):4402-4408.




Leney A.C., Xuxin F., Kitova E.N., Klassen J.S. Nanodiscs and electrospray ionization mass spectrometry: a tool for screening glycolipids against proteins. Anal. Chem. (2014) 86(11):5271-5277.


Leney A.C., Pashley C.L., Scarff C.S., Radford S.E., Ashcroft A.E. Insights into the role of the beta-2-microglobulin D-strand in amyloid propensity revealed by mass spectrometry. Mol. BioSyst. (2014) 10:412-420.




Leney A.C., McMorran, L.M., Radford, S.E., Ashcroft A.E. Amphipathic polymers enable the study of functional membrane proteins in the gas phase. Anal. Chem. (2012) 84(22):9841-9847.


Morrissey B., Leney A.C., Toste-Rego A., Allen W.J., Phan G., Waksman G., Ashcroft A.E., Radford S.E. The role of chaperone-subunit usher domain interactions in the mechanism of bacterial pilus biogenesis revealed by ESI-MS. Mol. Cell. Prot. (2012) 11:M111.015289.




Leney A.C., Phan G., Allen W., Verger D., Waksman G., Radford S.E., Ashcroft A.E. Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis. J. Am. Soc. Mass Spectrom. (2011) 22:1214-1223.

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